組蛋白ptm抗體特異性差是在表觀遺傳學(xué)研究中普遍存在的問題。snap-chip®驗證抗體使用epicypher專-利snap-chip®技術(shù)進(jìn)行檢測,確保ptm抗體具有極-高的特異性和ip效率。
圖中比較了使用低特異性(中)和高特異性(下)h3k4me3抗體的chip檢測結(jié)果。高特異性h3k4me2抗體作為參考對照(上)。
分析結(jié)果可發(fā)現(xiàn),當(dāng)使用低特異性抗體時,含有h3k4me3的基因組區(qū)域出現(xiàn)許多h3k4me2信號(灰色)。
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如需了解更多詳細(xì)信息或相關(guān)產(chǎn)品,請聯(lián)系epicypher中國授權(quán)代理商-欣博盛生物